Pathocultures

The relevance of "pathocultures" for research

To study how a novel preparation is metabolized within a diseased liver, the researcher needs pathologically modified cells. Further, with these cells in vitro patho-mechanisms can be simualted in vivo and diagnostic markers for disease can be discovered. Besides novel therapies for the given disease can be tested initially on such pathocultures representing this disease.

This means, deploying hepacult's pathocultures allows testing new medications which should fight liver disease on patients with certain liver damages for their efficacy and adverse effects.

By isolating liver cell fractions out of pathological material (liver cell tumour, HBV, HCV) strategies for the development of innovative therapies can be contrived.

Differences in the acquisition of cells

The extraction of the pathologically modified material requires a different approach compared to the acquisition of hepatocytes. The latter derive from tissue taken during liver resection. In contrast, cells for pathocultures are isolated from complete organs, which are substituted by a healthy new organ during liver explantation.

hepacult - market pioneer

Like the non-parenchymal cells "pathocultures" are market novelties. hepacult's spadework paves the way to use these cell types for specific research tasks and puts the company again ahead of the competition.